Relevant Publications

A bimolecular CO prodrug strategy

“A click-and-release approach to CO prodrugs.” Chemical Communications 50, no. 100 2014: 15890-15893

Unimolecular CO prodrugs using intramolecular DAinv reaction

“Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels-Alder Reaction” Angew. Chem. Int. Ed. Engl. 2016, 55, 15846-15851.

Enrichment triggered CO release within the mitochondria

“Enrichment-triggered Prodrug Activation Demonstrated through Mitochondria-targeted Delivery of Doxorubicin and Carbon Monoxide” Nature Chem. 2018, 10, 787-794.

pH-triggered CO prodrugs based on beta elimination

“pH-sensitive Metal-free Carbon Monoxide Prodrugs with Tunable and Predictable Release Rates” Chem. Commun. 2017, 53, 9628 – 9631.

ROS-triggered CO prodrugs based on beta elimination

“Organic CO prodrugs activated by endogenous ROS” Org. Lett. 2018, 20, 8-11.

Esterase-triggered CO prodrugs

“An Esterase-activated Click and Release Approach to Metal-free CO-prodrugs” Chem. Commun. 2017, 53, 8296-8299

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