Education

  1. Doctor of Philosophy (Bioinformatics): Georgia State University, Atlanta, Georgia, USA
  2. Master of Science (Computer Science): Georgia State University, Atlanta, Georgia, USA
  3. Master of Science (Biology): Georgia State University, Atlanta, Georgia, USA
  4. Master of Science (Bioinformatics): Western Kentucky University, Bowling Green, Kentucky, USA
  • Doctoral Dissertation:
    Goal: Identifying newer bioinformatics techniques for studying drug resistance in HIV & Staphylococcus aureus. Dissertation published here.
    Contributions: Application of machine learning techniques (Restricted Boltzmann Machine) on next generation sequencing, microarray datasets and structure guided drug design studies on HIV-1 protease. Application of algorithms was performed using R and Python functional programming languages while the structure guided drug design was studied using enzyme kinetics and X-ray crystallography. Our new technique of applying Restricted Boltzmann Machine produced highly accurate and robust classification of HIV protease resistance profiles. It was also used to effectively compare resistance profiles of different clinical protease inhibitors.
  • Master’s Degree (Computer Science) Project:
    Goal: Computational optimization of defined graph-based sequence structure HIV-1 protease resistance prediction through supervised, unsupervised machine learning techniques.
    Contributions: Application of supervised and unsupervised clustering techniques on next generation sequencing datasets for identifying representative HIV-1 protease sequences.
  • Master’s Degree (Bioinformatics) Project:
    Goal: Transcriptomic data analysis to determine the impact of antioxidant supplementation on gene expression in brains of mice infected with T. gondii.
    Contributions: Application of linear transformations like data driven Haar-Fisz transformations on microarray datasets for identifying gene expression trends.
  • Relevant Computer Science coursework at Georgia State University:

Automata (Prof Li), Theoretical Foundations of Computer Science (Prof Zelikowsky), Data Structures (Prof Bhola), Operating Systems, Advanced Bioinformatics (Prof Harrison), Fundamentals of Bioinformatics (Prof Harrison), Principles of Computer Science (Prof Henry), UNIX/C for Bioinformatics, Seminar in Computer Science, Design & Analysis of Algorithms (Prof Skums), Mobile App Development, Web Programming (Bing Li), Advanced Bioinformatics (Prof Zelikowsky), Programming Language Concepts (Prof Mussa), Software Engineering(Prof Bhola), Advanced Software Engineering (Prof Hu), Advanced Graphics Algorithms (Prof Zhu), Computer Architecture (Prof Belkasim), Advanced Algorithms for Bioinformatics (Prof Zelikowsky).

  • Relevant Biology coursework at Georgia State University:

Molecular Immunology, Concepts Molecular Genetics, Advanced Biotechniques, Physiology Prokaryotes, Concepts Cell Biology.

  • Relevant Bioinformatics coursework at Western Kentucky University:

Biostatistics, Bioinformatics, Epidemiology, Public Health, Health Behavior, Topics in Immunology, Advanced Molecular Genetics, Parasitology, Advanced Biochemistry, Virology.