Precursor Metabolites (Intermediates)-

• Glycolysis
  • Glucose 6-Phosphate
    • Results from glucose being phosphorylated by ATP
  • Fructose 6-phophate
    • Results from Glucose 6- P being isomerized
  • Fructose 1,6- Phosphate
    • Results from Fructose 6- P being phosphorylated
  • Glyceraldehyde 3-phophate and dihydroxyacetone phosphate
    • Results from the enzyme aldose splitting fructose 1,6- bisphosphoglyceric acid
  • 1,3- Biphosphoglycerate
    • Results from the oxidation of glyceraldehyde 3- phosphate
  • 3-P-Glycerate
    • ATP synthesized when 1,3- Bisphosphoglyceric acid is converted to 3-phosphoglyceric acid
    • Glycine and Cysteine amino acids
  • Citric acid cycle intermediates
    • α- ketoglutarate and Oxaloacetate are precursors of amino acids
      • Proline, Glutamine, and Arginine
    • Oxaloacetate
      • also a precursor to phosphoenolpyruvate, precursor of glucose
      • Asparagine, Lysine, Methionine, Threonine, Isoleucine
    • Succinyl-CoA
      • Precursor of cytochromes and chlorophyll
    • Acetyl-CoA
      • Precursor of fatty acid biosynthesis
    • Glyoxylate cycle
      • Glyoxylate intermediate
    • Adenosine diphosphoglucose
      • Precursor for glucose biosynthesis
    • Uridine diphosphoglucose
      • Precursor of some glucose derivatives needed for biosynthesis of polysaccharides