Services

The MS Facility is well equipped to do both qualitative and quantitative mass spectrometric analysis of macromolecules such as proteins, peptides, oligonucleotides, lipids, and carbohydrates and small molecules with separation capabilities using chromatographic techniques.

Mass Spectrometers Ionization Mass Analyzer Application
Xevo-G2-xs Q-TOF Mass spectrometer with I class  Acquity UPLC

(Waters )

 ESI

APCI

 Quadruple-TOF
  • Nominal mass measurements
  • Accurate mass measurements (1 ppm accuracy)
  • Elemental composition analyses
  • Tandem mass measurements
  • Protein characterization and identification
  • Quantitative analysis
Axima Confidence

(Shimadzu)

 MALDI TOF
  • Mass determinations of intact proteins, peptides, oligonuclotides, glycolipids, carbohydrates and other small organic molecules.
Xevo TQ-s micro

(Waters)

 ESI

APCI

 Triple Quadruple
  • Nominal mass measurements
  • Tandem mass measurements
  • Liquid chromatographic separations
  • Quantitative analyses (MRM)
5973 network MS with 6890N networkGC system 

(Agilent)

 EI

CI

 Quadrupole
  • Nominal mass measurements
  • Gas chromatographic separations
  • Quantitative analyses
  • Library search

 

Instrument Mode I Mode II Applications
Monolith X
(NanoTemper)		 Spectra Shift Microscale Thermophoresis
(MST)
  • Small-molecule binding events
  • Protein-protein interactions.
  • Multi-protein complex interactions.