Instruments

AXIMA Confidence : Shimadzu Scientific Instruments
https://www.ssi.shimadzu.com/products/maldi/ms/axima-confidence/index.html

Mass spectrometer

The Shimadzu’s AXIMA Confidence is a MALDI-Tof mass spectrometer with both linear and reflectron modes for mass measurement of both small and large molecules with high resolution and mass accuracy necessary for successful proteomics and life science experiments. Linear mode allows the interrogation of high molecular weight samples. It is featured for high throughput analysis.

The Waters Xevo-g2-xs
https://www.waters.com/waters/en_US/Xevo-G2-XS-QTof-Quadrupole-Time-of-Flight-Mass-Spectrometer/nav.htm?cid=134798222&locale=en_US
https://www.waters.com/webassets/cms/library/docs/720005074en.pdf

Mass Spectrometer

The Waters Xevo-G2-xs Q-Tof mass spectrometer can provide both routine structural elucidation of small molecules and biomacromolecules as well as exact mass measurements with both Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) ion sources. It is coupled with Acquity I class UPLC which provides quantitative analysis. The instrument also features a quadruple mass filter and collision cell for MS/MS analyses.

The Waters’ Xevo TQ-s micro
https://www.waters.com/waters/en_US/Xevo-TQ-S-micro-Triple-Quadrupole-Mass-Spectrometry/nav.htm?cid=134798856&locale=en_US

Mass spectrometer

The Xevo TQ-s micro LC/MS/MS system is a triple quadruple mass spectrometer coupled with a Waters Acquity H class UPLC and UV-DAD used ideally for qualitative and quantitative analysis of chemical and biological molecules (M/Z < 1800 Da).

The NanoTemper’s MONOLITH X
https://nanotempertech.com/monolith/

Mass spec

Monolith X is an analytical tool to measure binding affinities between a wide range of targets and ligands in solution. It works through spectrum shift technology or microscale thermophoresis technology (MST) which doesn’t require samples to be bound on chips. The applications cover from small-molecule binding events to protein-protein interactions as well as multi-protein complexes interactions.