1684- Leuwenhoek’s microscope finds first microorganism

1843- Rumen ciliate protozoa is first reported

1860- Pasteur denies natural occurrence of microorganisms

1875- Ferdinand J. Cohn publishes a journal in which he first classifies bacteria as Bacillus

1876- Robert Koch publishes a paper about a bacterium being the cause of anthrax

1878- Joseph Lister publishes his results of his study on lactic fermentation of milk. His research used the first method developed to isolate pure culture of bacterium

1880- Louis Pasteur attenuates the pathogen that causes chicken cholera

1881- Robert Koch creates a solid culture medium for bacteria

1884- Robert Koch wins a noble prize for The Etiology of Tuberculosis

1885- Louis Pasteur injects a child with rabies virus.

1889- Martinus Beijerinck obtains a pure culture of Rhizohium

1892- Dmitri Iosifovich Ivanovski discovers viruses

1899- Martinus Beijerinck recognizes viral dependence on cells for reproduction

1900- Walter Reed proves mosquitoes carried the yellow fever agent

1910- Paul Ehrich discovers cure for syphilis

1928- Alexander Fleming discovers Penicillin

1977- Gilbert and Sanger develop a method to sequence DNA

1983- Kary Mulls invents Polymerase Chain Reaction

1995- First microbial genomic sequence published